CD18 adhesion blockade decreases bacterial clearance and neutrophil recruitment after intrapulmonary E. coli , but not after S. aureus
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چکیده
منابع مشابه
CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke.
BACKGROUND AND PURPOSE Neutrophil (PMN) recruitment mediated by increased expression of intercellular adhesion molecule-1 expression (ICAM-1, CD54) in the cerebral microvasculature contributes to the pathogenesis of tissue injury in stroke. However, studies using blocking antibodies against the common beta2-integrin subunit on the PMN, the counterligand for ICAM-1 (CD18), have demonstrated equi...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 1997
ISSN: 0741-5400
DOI: 10.1002/jlb.61.2.167